People facing multiple disadvantage experience a combination of problems including homelessness, substance misuse, contact with the criminal justice system and mental ill health. They fall through the gaps between services and systems, making it harder for them to address their problems and lead fulfilling lives. Making Every Adult Matter (MEAM) is a unique coalition of the national charities Clinks, Collective Voice, Homeless Link and Mind. Together MEAM represents over 1,300 frontline organisations across England. MEAM supports local areas across the country to transform services and systems and to directly improve the lives of people facing multiple disadvantage. We use our shared knowledge and practical experience from this work to influence policy at the national and local level.